Anti-HRP-2 Mab

HRP2 is a surface malaria protein. The antigen is expressed only by P. falciparum trophozoites. It is a histidine- and alanine-rich protein, which is localized in several cell compartments including the parasite cytoplasm.


It is characterized by many contiguous repeats of the sequences AHH and AHHAAD. The histidine-rich protein 2 from P. falciparum has been implicated as a heme polymerase that detoxifies free heme by its polymerization to inactive hemozoin.

This antibody is raised against recombinant HRPII. It is purified from in vitro-produced supernatant, by Protein G Antibody affinity chromatography.